منابع مشابه
Vitamin-Induced Hemolysis
Case Summary A 47 year-old African American man presented to the hospital with three a day history of fever, shortness of breath, nausea, emesis, dark urine, and progressive confusion. The symptoms began one day following an infusion of a “vitamin complex” at his physician’s office. The patient’s medical history was significant for retroperitoneal fibrosis with multiple urological procedures, f...
متن کاملCobra Venom-induced Hemolysis
Interest in the alternate or C3 shunt complement pathway has recently been generated by a number of reports (1-5). Its presence in invertebrates points to a primitive phylogenetic appearance (6). The C3 shunt can be triggered by high molecular weight polysaccharides in a manner reminiscent of the properdin system (7). Once activated by cobra venom, erythrocytes and other cells can be lysed in t...
متن کاملSitagliptin, sitagliptin and metformin, or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats
Diabetic neuropathies are a family of nerve disorders caused by diabetes. Symptoms of the disease include nerve palsy, mononeuropathy, mononeuropathy multiplex, diabetic amyotrophy, painful polyneuropathy, autonomic neuropathy, and thoracoabdominal neuropathy. In this study, type 2 diabetes in rats was induced with nicotinamide-streptozotocin. Drug treatment was initiated on the d 15, with the ...
متن کاملSitagliptin Inhibits the Lipopolysaccharide-Induced Inflammation
Objective: Sitagliptin is an anti-diabetic Dipeptidyl peptidase-4 (DPP-4) inhibitor; used worldwide with a well-established evidence base as an effective anti-diabetic therapy and the lowest cost of all DPP-4 inhibitors. Atherosclerosis and inflammation are more common in diabetic patients than in nondiabetic patients, and progression of atherosclerosis contributes to this inflammation. Therefo...
متن کاملMechanism of hemolysis induced by ferriprotoporphyrin IX.
Incubation of a 0.5% suspension of washed, normal mouse erythrocytes with ferriprotoporphyrin IX (FP) at 37 degrees C and pH 7.4 caused potassium loss, swelling, increased susceptibility to hypotonic lysis, and finally hemolysis. Hemolysis was not inhibited by incubation in the dark, malonyldialdehyde was not produced, and various free radical scavengers had no effect on the hemolysis. Only the...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmacology
سال: 2010
ISSN: 0253-7613
DOI: 10.4103/0253-7613.70405